Yuya Horinouchi Selected Research

Hypoxia (Hypoxemia)

1/2018	Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate.
1/2017	Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation.

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Yuya Horinouchi Research Topics

Disease

6	Neoplasms (Cancer) 09/2021 - 10/2014
5	Hypertension (High Blood Pressure) 01/2021 - 01/2009
5	Cardiovascular Diseases (Cardiovascular Disease) 03/2020 - 08/2015
4	Fibrosis (Cirrhosis) 05/2023 - 01/2014
4	Inflammation (Inflammations) 01/2020 - 01/2012
4	Anemia 01/2020 - 01/2017
3	Obesity 01/2020 - 01/2012
2	Chronic Renal Insufficiency 05/2023 - 01/2018
2	Ureteral Obstruction 05/2023 - 01/2014
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2011
2	Atherosclerosis 03/2020 - 07/2010
2	Aortic Aneurysm (Aneurysm, Aortic) 03/2020 - 01/2018
2	Vascular Remodeling 12/2019 - 01/2013
2	Drug-Related Side Effects and Adverse Reactions 03/2019 - 01/2019
2	Hypertrophy 01/2019 - 01/2012
2	Atrophy 01/2019 - 05/2016
2	Iron Overload 01/2019 - 01/2019
2	Hypoxia (Hypoxemia) 01/2018 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2015 - 10/2014
1	Hypertriglyceridemia 05/2023
1	Seizures (Absence Seizure) 07/2021
1	Epilepsy (Aura) 07/2021
1	Nausea 01/2021
1	Vomiting 01/2021
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Vascular Calcification 03/2020
1	Iron Deficiencies 01/2020
1	Insulin Resistance 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020
1	Neutropenia 03/2019
1	Ovarian Neoplasms (Ovarian Cancer) 03/2019
1	Rupture 01/2019
1	Aortic Dissection 01/2019
1	Albuminuria 01/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2019

Drug/Important Bio-Agent (IBA)

10	IronIBA 01/2020 - 01/2012
4	Angiotensin IIIBA 12/2019 - 07/2010
3	nitrosonifedipineIBA 01/2018 - 01/2013
3	Free RadicalsIBA 01/2015 - 01/2011
2	Cisplatin (Platino)FDA LinkGeneric 09/2021 - 01/2021
2	Bevacizumab (Avastin)FDA Link 01/2021 - 01/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2011
2	Irinotecan (Camptosar)FDA LinkGeneric 03/2019 - 01/2011
2	AminopropionitrileIBA 01/2019 - 01/2018
2	Chelating AgentsIBA 01/2019 - 01/2014
2	Ligases (Synthetase)IBA 01/2019 - 05/2016
2	Superoxides (Superoxide)IBA 01/2019 - 01/2011
2	UbiquitinIBA 01/2019 - 05/2016
2	Messenger RNA (mRNA)IBA 01/2018 - 05/2016
2	Ferritins (Ferritin)IBA 01/2018 - 08/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 07/2010
2	aniline (aniline hydrobromide)IBA 01/2015 - 10/2014
2	4-nitrosodimethylanilineIBA 01/2015 - 10/2014
2	nitrosobenzeneIBA 01/2015 - 10/2014
2	N,N-dimethylanilineIBA 01/2015 - 10/2014
2	Deferoxamine (Desferal)FDA LinkGeneric 01/2014 - 01/2012
1	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 05/2023
1	Hemoglobins (Hemoglobin)IBA 05/2023
1	PPAR alphaIBA 05/2023
1	Adenine FDA LinkGeneric 05/2023
1	Fibric Acids (Fibrates)IBA 05/2023
1	CreatinineIBA 05/2023
1	Urea (Carbamide)FDA LinkGeneric 05/2023
1	NitrogenIBA 05/2023
1	Antineoplastic Agents (Antineoplastics)IBA 09/2021
1	Anticonvulsants (Antiepileptic Drugs)IBA 07/2021
1	Valacyclovir (Valtrex)FDA LinkGeneric 07/2021
1	Pentylenetetrazole (Metrazol)IBA 07/2021
1	Levetiracetam (Keppra)FDA LinkGeneric 07/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Palonosetron (Aloxi)FDA Link 01/2021
1	Diphenhydramine (Benadryl)FDA LinkGeneric 01/2021
1	XELOXIBA 01/2021
1	Omeprazole (Prilosec)FDA LinkGeneric 01/2021
1	Serotonin (5 Hydroxytryptamine)IBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 03/2020
1	Cyclophilin AIBA 03/2020
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 03/2020
1	Proton Pump InhibitorsIBA 01/2020
1	ApoferritinsIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Rubber (Elastica)IBA 12/2019
1	Febuxostat FDA Link 12/2019
1	Xanthine OxidaseIBA 12/2019
1	Uric Acid (Urate)IBA 12/2019
1	pitavastatin (itavastatin)FDA Link 01/2019
1	arginine methyl esterIBA 01/2019
1	tempolIBA 01/2019
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2019
1	Dietary IronIBA 01/2019
1	Hydroxyl RadicalIBA 01/2019
1	edoxabanIBA 07/2018
1	IndicanIBA 01/2018
1	artemisinin (artemisinine)IBA 01/2018
1	Nifedipine (Adalat)FDA LinkGeneric 01/2018
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2018
1	HepcidinsIBA 01/2018

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2021 - 04/2015